Oxford Cases In Medicine And Surgery Pdf Download

Oxford Cases In Medicine And Surgery Pdf Download

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Gitlitz et al. also presented an observational case-control study in which the authors investigated the effectiveness of adenotonsillectomy in reducing episodes of PFAPA in 23 patients compared with 24 children with another form of periodic fever [35]. The authors defined a PFAPA episode as an episode that had not resolved after 12 weeks of symptomatic therapy. They found similar frequencies of spontaneous resolution of fever episodes in both groups. However, in the adenotonsillectomy group, there were significantly more episodes resolved by 6 months of follow-up, which persisted at 12 months (P = 0.02). The authors concluded that the presence of tonsils and adenoids could be a source of triggering factors that may have contributed to the diagnosis of PFAPA in children who were initially believed to have an alternative diagnosis. Moreover, the presence of tonsils and adenoids may be associated with a more prolonged course of PFAPA. The authors concluded that adenotonsillectomy should be considered in children with PFAPA when other possible causes of PFAPA have been excluded.

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